The HPE ProLiant ML100 series (featuring the ML110 Gen10 & Gen11) provides "right-sized" performance for SMBs and remote offices. This 4.5U tower series delivers high-compute power and vast expandability without the need for a dedicated server room.
Compute: Supports Intel® Xeon® Scalable processors (up to 32 cores) for intensive workloads.
Memory & Speed: High-bandwidth DDR5 SmartMemory and PCIe Gen5 support for future-proofed data throughput.
Storage Flexibility: Scalable configurations supporting up to 16 SFF or 8 LFF hot-plug drives (NVMe/SAS/SATA).
Security: Industry-leading protection via HPE Silicon Root of Trust and iLO 6 management.
Optimized For: Virtualization, edge computing, file/print, and small-scale database management.

The HPE ProLiant ML110 Gen11 Server is a robust, single-processor tower server designed to meet the demands of small to medium-sized businesses. With its balance of performance, expandability, and reliability, it serves as an ideal solution for growing enterprises seeking a dependable IT infrastructure.
Key Features:
Processor: Intel Xeon 3508U 2.1GHz 8-core processor
Memory: 32GB DDR4 Registered (RDIMM)
Storage: 4 Large Form Factor (LFF) drive bays with 2x2TB HDDs
RAID Support: Integrated VROC for flexible RAID configurations
Power Supply: Dual 1000W Redundant Power Supplies (RPS)
Form Factor: Tower server suitable for office environments
Network: Integrated Gigabit Ethernet for reliable connectivity
What's New:
Introduction of the Intel Xeon 3508U processor for enhanced performance
Support for up to 4 LFF drives, providing scalable storage options
Dual 1000W RPS for improved power redundancy and reliability
Enhanced memory capacity with 32GB DDR4 RDIMM, expandable as needed
Optimized for small to medium-sized business workloads and applications
Performance and Scalability
The HPE ProLiant ML110 Gen11 Server is equipped with an Intel Xeon 3508U 8-core processor, delivering robust performance for a variety of business applications. With 32GB of DDR4 RDIMM memory, it ensures smooth multitasking and efficient handling of workloads.
Storage and Expansion
Featuring 4 LFF drive bays and pre-installed with 2x2TB HDDs, the server offers ample storage capacity for growing data needs. The integrated VROC RAID support provides flexibility in configuring storage for redundancy or performance.
Reliability and Power Efficiency
The inclusion of dual 1000W Redundant Power Supplies ensures continuous operation and minimizes downtime, enhancing the server's reliability. Its tower form factor allows for easy integration into office environments without the need for dedicated server rooms.
Networking and Connectivity
With integrated Gigabit Ethernet, the server offers reliable network connectivity, essential for business operations that require consistent and fast data transfer.
I/O Diagram (Front)
Key
Component
1
DisplayPort 1.1a
2
USB 3.2 Gen1 port
3
iLO service port
4
UID button/LED
5
NIC status LED
6
Health LED
7
Power on/Standby button and system power LED
8
Optical drive bay
9
Media Bay: optional internal USB RDX docking station
10
Box1: 4LFF/NHP or 8SFF SAS/SATA drive cage
11
Box2: Optional 4LFF/NHP or 8SFF SAS/SATA drive cage
Note: Image shown without the security front bezel which is standard in every ML110 Gen11 unit.
I/O Diagram (Side)
Key
Component
1
CPU Socket with 16 DDR5 DIMM slots
2
M.2 Slot 2
3
M.2 Slot 1
4
x8 SlimSAS port
5
Megacell battery holder (Under)
6
HPE NS204i-u NVMe Hot Plug Boot Device (Optional)
7
Slot 14 OCP 1 (Optional for OROC/NIC)
8
Slot 4 PCIe5 x16
9
USB 2.0 port
10
Slot 1 PCIe5 x16
11
MCIO port 1 for the riser slot 2
12
MCIO port 2 for the riser slot 2
13
MCIO port 3 for the riser slot 3
14
MCIO port 4 for the riser slot 3
15
USB 3.2 Gen 1 port
I/O Diagram (Back)
Key
Component
1
HPE NS204i-u Gen11 NVMe Hot Plug Boot Device (Optional)
2
Flexible Slot power supply 1
3
Flexible Slot power supply 2
4
Slot 14 OCP 1 (Optional for OROC/NIC OCP adapter)
5
Serial port (Optional)
6
VGA Port
7
Dual USB 3.2 Gen 1 ports
8
iLO management port
9
Dual NIC ports (1 GbE)
10
Slot 1 PCIe5 x16
11
Slot 2 PCIe5 x16 (Optional riser kit required)
12
Slot 3 PCIe5 x16 (Optional riser kit required)
13
Slot 4 PCIe5 x16

The HPE ProLiant ML110 Gen11 is a reliable and scalable tower server tailored for small to mid-sized businesses needing dependable compute, storage, and remote management capabilities. Powered by a single 8-core Intel Xeon Bronze 3508U processor and equipped with dual 480 GB SATA SSDs, this system is ideal for handling essential workloads while providing headroom for future expansion. Housed in a compact 4.5U tower chassis and backed by redundant 1000W power supplies, it’s designed to run business-critical tasks efficiently and securely without compromise.
Key Features
Intel Xeon Bronze 3508U processor with 8 cores, 2.1 GHz base, and 2.2 GHz boost speeds
22.5 MB processor cache for improved data handling and multitasking
32 GB DDR5-SDRAM (1 x 32 GB) with 5600 MHz memory clock speed
Dual 480 GB 2.5" SATA III SSDs included, supporting RAID and scalable up to 8 SSDs
Gigabit Ethernet connectivity with 2 x RJ-45 LAN ports
Redundant 1000W power supplies installed (total 2000W capacity)
Chassis design: Tower (4.5U), black finish, dimensions 183mm x 630mm x 600mm
No pre-installed operating system — ideal for custom deployments
Optimized Entry-Level Performance
Powered by the Intel Xeon Bronze 3508U, the ML110 Gen11 provides dependable compute with 8 physical cores and solid cache capacity. It’s a solid choice for light virtualization, file serving, and office-critical applications.
Enterprise Storage Flexibility
This configuration includes 2 x 480 GB 2.5" SATA SSDs with RAID capability. The system supports up to 8 SSDs, giving you options to scale storage as your business data grows while maintaining data protection.
Robust Network and Power Architecture
Dual Gigabit Ethernet ports ensure reliable network performance for local and remote operations. Built-in redundant power supplies with a combined 2000W capacity offer high availability, ensuring business continuity even during power-related failures.
Tool-Free, Customizable Design
With a 4.5U chassis and no preloaded operating system, the server offers excellent deployment flexibility. It’s ideal for businesses needing to install their own preferred OS environment or server stack.
I/O Diagram (Front)
Key
Component
1
DisplayPort 1.1a
2
USB 3.2 Gen1 port
3
iLO service port
4
UID button/LED
5
NIC status LED
6
Health LED
7
Power on/Standby button and system power LED
8
Optical drive bay
9
Media Bay: optional internal USB RDX docking station
10
Box1: 4LFF/NHP or 8SFF SAS/SATA drive cage
11
Box2: Optional 4LFF/NHP or 8SFF SAS/SATA drive cage
Note: Image shown without the security front bezel which is standard in every ML110 Gen11 unit.
I/O Diagram (Side)
Key
Component
1
CPU Socket with 16 DDR5 DIMM slots
2
M.2 Slot 2
3
M.2 Slot 1
4
x8 SlimSAS port
5
Megacell battery holder (Under)
6
HPE NS204i-u NVMe Hot Plug Boot Device (Optional)
7
Slot 14 OCP 1 (Optional for OROC/NIC)
8
Slot 4 PCIe5 x16
9
USB 2.0 port
10
Slot 1 PCIe5 x16
11
MCIO port 1 for the riser slot 2
12
MCIO port 2 for the riser slot 2
13
MCIO port 3 for the riser slot 3
14
MCIO port 4 for the riser slot 3
15
USB 3.2 Gen 1 port
I/O Diagram (Back)
Key
Component
1
HPE NS204i-u Gen11 NVMe Hot Plug Boot Device (Optional)
2
Flexible Slot power supply 1
3
Flexible Slot power supply 2
4
Slot 14 OCP 1 (Optional for OROC/NIC OCP adapter)
5
Serial port (Optional)
6
VGA Port
7
Dual USB 3.2 Gen 1 ports
8
iLO management port
9
Dual NIC ports (1 GbE)
10
Slot 1 PCIe5 x16
11
Slot 2 PCIe5 x16 (Optional riser kit required)
12
Slot 3 PCIe5 x16 (Optional riser kit required)
13
Slot 4 PCIe5 x16

The HPE ProLiant ML110 Gen11 (P77234-425) is designed for powerful performance in a compact tower form factor. Featuring a 12-core Intel® Xeon® Silver 4510 processor at 2.4 GHz (boosting to 4.1 GHz), this server includes 32 GB of DDR5 memory running at 5600 MHz. With the Intel C741 chipset, it delivers enterprise-class performance for growing businesses. The system comes with 8 TB of pre-installed SATA storage (2x 4 TB HDDs), supports RAID, and allows expansion up to 192 TB. Dual Gigabit Ethernet, redundant 1000W power supplies, and a rack-convertible chassis round out this balanced and reliable solution.
Key Features:
Intel® Xeon® Silver 4510 processor (12 cores, 2.4 GHz base, 4.1 GHz boost, 30 MB cache)
32 GB DDR5-SDRAM installed (1 x 32 GB), up to 1.5 TB across 16 DIMM slots
High-speed memory at 5600 MHz, delivering improved bandwidth and energy efficiency
Includes 2 x 4 TB SATA HDDs, expandable to 192 TB total storage capacity
Supports 4 LFF 3.5" drives with RAID capability for data protection
Intel C741 chipset and PCIe Gen5 architecture for modern workload demands
Dual Gigabit Ethernet with Broadcom 5720 controller for fast, stable networking
Redundant 1000W power supply units included for failover and operational stability
TPM 2.0 security module integrated for secure system startup and operations
Compact 4.5U tower chassis; rack-convertible using 5.5U space
Tailored Compute Power
This ML110 Gen11 model runs on a single Intel® Xeon® Silver 4510 processor delivering a balance of 12-core multi-threaded performance with 30 MB cache, ideal for virtualized workloads, file sharing, ERP/CRM systems, and VDI. It leverages DDR5 memory at 5600 MHz to support advanced application requirements and reduce latency under load.
Flexible Storage Capacity
Preloaded with two 4 TB 3.5" SATA drives and built to scale, the server supports up to 4 LFF drives with RAID, enabling growth to 192 TB maximum capacity. It offers reliable, protected data handling for storage-intensive environments while remaining energy-conscious and space-efficient.
Enterprise-Ready Networking and Expansion
Featuring dual Gigabit Ethernet via Broadcom 5720 and multiple high-speed USB 3.2 ports, the server ensures reliable connectivity and ease of device integration. Expand performance capabilities with multiple PCIe Gen5 slots, providing ample bandwidth for storage controllers, graphics accelerators, or networking cards.
Smart Power and Security Integration
The system is equipped with two 1000W redundant power supplies to ensure consistent uptime and failover protection. With TPM 2.0 onboard, system integrity and secure boot processes are standard. The server's intelligent design promotes reliability, manageability, and peace of mind for IT administrators handling critical infrastructure.
I/O Diagram (Front)
Key
Component
1
DisplayPort 1.1a
2
USB 3.2 Gen1 port
3
iLO service port
4
UID button/LED
5
NIC status LED
6
Health LED
7
Power on/Standby button and system power LED
8
Optical drive bay
9
Media Bay: optional internal USB RDX docking station
10
Box1: 4LFF/NHP or 8SFF SAS/SATA drive cage
11
Box2: Optional 4LFF/NHP or 8SFF SAS/SATA drive cage
Note: Image shown without the security front bezel which is standard in every ML110 Gen11 unit.
I/O Diagram (Side)
Key
Component
1
CPU Socket with 16 DDR5 DIMM slots
2
M.2 Slot 2
3
M.2 Slot 1
4
x8 SlimSAS port
5
Megacell battery holder (Under)
6
HPE NS204i-u NVMe Hot Plug Boot Device (Optional)
7
Slot 14 OCP 1 (Optional for OROC/NIC)
8
Slot 4 PCIe5 x16
9
USB 2.0 port
10
Slot 1 PCIe5 x16
11
MCIO port 1 for the riser slot 2
12
MCIO port 2 for the riser slot 2
13
MCIO port 3 for the riser slot 3
14
MCIO port 4 for the riser slot 3
15
USB 3.2 Gen 1 port
I/O Diagram (Back)
Key
Component
1
HPE NS204i-u Gen11 NVMe Hot Plug Boot Device (Optional)
2
Flexible Slot power supply 1
3
Flexible Slot power supply 2
4
Slot 14 OCP 1 (Optional for OROC/NIC OCP adapter)
5
Serial port (Optional)
6
VGA Port
7
Dual USB 3.2 Gen 1 ports
8
iLO management port
9
Dual NIC ports (1 GbE)
10
Slot 1 PCIe5 x16
11
Slot 2 PCIe5 x16 (Optional riser kit required)
12
Slot 3 PCIe5 x16 (Optional riser kit required)
13
Slot 4 PCIe5 x16

The HPE ProLiant ML110 Gen11 5416S 2.0GHz 16-core 1P 32GB-R VROC 8SFF 1000W RPS Server is engineered to deliver robust performance and scalability for small to medium-sized businesses. With its powerful processing capabilities and flexible configuration options, it is well-suited for various workloads, including virtualization, data management, and business applications.
Key Features:
Processor: Intel Xeon Gold 5416S 2.0GHz 16-core processor
Memory: 32GB DDR5 Registered (RDIMM)
Storage Controller: Intel VROC SATA/NVMe support
Drive Bays: 8 Small Form Factor (SFF) drive bays
Power Supply: 1000W Flex Slot Titanium Hot Plug Power Supply
Form Factor: Tower server with optional rack conversion
Network: Embedded 2-Port 1GbE BCM5720 networking ports
What's New:
Integration of Intel Xeon Gold 5416S processor for enhanced performance
Support for up to 8 SFF drives, providing scalable storage options
Enhanced energy efficiency with a 1000W Flex Slot Titanium Hot Plug Power Supply
Optimized for small to medium-sized business workloads and applications
Performance and Scalability
Equipped with the Intel Xeon Gold 5416S 16-core processor and 32GB of DDR5 RDIMM memory, the HPE ProLiant ML110 Gen11 ensures reliable performance for demanding business tasks. Its scalable architecture allows for future upgrades to meet growing business demands.
Storage and Expansion
The server features 8 SFF drive bays, providing ample storage capacity for data-intensive applications. With Intel VROC support, businesses can configure RAID setups directly through the CPU, eliminating the need for separate RAID controllers.
Reliability and Power Efficiency
The inclusion of a 1000W Flex Slot Titanium Hot Plug Power Supply ensures continuous operation and minimizes downtime, enhancing the server's reliability. Its tower form factor allows for easy integration into office environments without the need for dedicated server rooms.
Networking and Connectivity
Designed with embedded 2-Port 1GbE BCM5720 networking ports, the server offers reliable connectivity essential for business operations that require consistent and fast data transfer.
I/O Diagram (Front)
Key
Component
1
DisplayPort 1.1a
2
USB 3.2 Gen1 port
3
iLO service port
4
UID button/LED
5
NIC status LED
6
Health LED
7
Power on/Standby button and system power LED
8
Optical drive bay
9
Media Bay: optional internal USB RDX docking station
10
Box1: 4LFF/NHP or 8SFF SAS/SATA drive cage
11
Box2: Optional 4LFF/NHP or 8SFF SAS/SATA drive cage
Note: Image shown without the security front bezel which is standard in every ML110 Gen11 unit.
I/O Diagram (Side)
Key
Component
1
CPU Socket with 16 DDR5 DIMM slots
2
M.2 Slot 2
3
M.2 Slot 1
4
x8 SlimSAS port
5
Megacell battery holder (Under)
6
HPE NS204i-u NVMe Hot Plug Boot Device (Optional)
7
Slot 14 OCP 1 (Optional for OROC/NIC)
8
Slot 4 PCIe5 x16
9
USB 2.0 port
10
Slot 1 PCIe5 x16
11
MCIO port 1 for the riser slot 2
12
MCIO port 2 for the riser slot 2
13
MCIO port 3 for the riser slot 3
14
MCIO port 4 for the riser slot 3
15
USB 3.2 Gen 1 port
I/O Diagram (Back)
Key
Component
1
HPE NS204i-u Gen11 NVMe Hot Plug Boot Device (Optional)
2
Flexible Slot power supply 1
3
Flexible Slot power supply 2
4
Slot 14 OCP 1 (Optional for OROC/NIC OCP adapter)
5
Serial port (Optional)
6
VGA Port
7
Dual USB 3.2 Gen 1 ports
8
iLO management port
9
Dual NIC ports (1 GbE)
10
Slot 1 PCIe5 x16
11
Slot 2 PCIe5 x16 (Optional riser kit required)
12
Slot 3 PCIe5 x16 (Optional riser kit required)
13
Slot 4 PCIe5 x16

Built for demanding SMB workloads, the HPE ProLiant ML110 Gen11 featuring the Intel Xeon Silver 4514Y processor brings enterprise-level performance to a compact tower chassis. With a base frequency of 2.0 GHz, turbo boost up to 3.4 GHz, and 16 cores, it’s engineered to support scalable computing needs. Enhanced with 64 GB DDR5 memory, dual 480 GB SATA SSDs, and redundant power options, this 4.5U tower server delivers reliable performance, flexible expansion, and secure remote management for branch offices and growing infrastructure environments.
Key Features:
Intel Xeon Silver 4514Y processor with 16 cores, 30 MB cache, 2.0 GHz base and 3.4 GHz boost speeds
64 GB DDR5-SDRAM (2 x 32 GB modules) with 5600 MHz memory clock, expandable to 1.5 TB via 16 DIMM slots
Dual 480 GB SATA III SSDs (2.5") installed; supports up to 8 SSDs with RAID capabilities
Broadcom 5720 Gigabit Ethernet with two RJ-45 ports for stable and efficient network connectivity
4.5U tower chassis design with active cooling, rack-mountable with 5.5U conversion kit
Advanced PCIe Gen5 expandability: 4 x16 slots and 1 x16 OCP 3.0 slot for future upgrades
HPE iLO 6 for comprehensive remote management, monitoring, and system updates
Dual 1000W power supplies (1+1 redundancy) to ensure system uptime and failover protection
Rear I/O ports: 2 x Gigabit Ethernet, 3 x USB 3.2 Gen 1, 1 x VGA, 1 x DisplayPort
Precision Computing with Intel Xeon Silver 4514Y
Experience robust processing with Intel’s Xeon Silver 4514Y, delivering 16-core parallelism and high-speed responsiveness for multi-threaded business applications, virtualization, and database management tasks.
Memory That Adapts to Your Growth
Outfitted with 64 GB of DDR5 memory, the ML110 Gen11 supports a maximum of 1.5 TB across 16 DIMM slots. This future-ready memory configuration ensures your infrastructure remains responsive as workload demands scale.
Secure Storage with RAID Flexibility
Dual 480 GB SSDs offer fast data access and enhanced durability. With support for up to 8 SSDs and integrated RAID options, the server allows for scalable, secure storage tailored to your organization’s data footprint.
Power Redundancy in a Compact Tower
Designed for mission-critical uptime, the server comes with dual 1000W redundant power supplies and active cooling. The 4.5U black tower chassis fits easily into tight IT spaces or racks with minimal conversion effort.
Remote Control Made Easy with iLO 6
Monitor, configure, and troubleshoot your server remotely with HPE iLO 6, allowing IT administrators to maintain control and visibility from virtually anywhere without compromising security.
I/O Diagram (Front)
Key
Component
1
DisplayPort 1.1a
2
USB 3.2 Gen1 port
3
iLO service port
4
UID button/LED
5
NIC status LED
6
Health LED
7
Power on/Standby button and system power LED
8
Optical drive bay
9
Media Bay: optional internal USB RDX docking station
10
Box1: 4LFF/NHP or 8SFF SAS/SATA drive cage
11
Box2: Optional 4LFF/NHP or 8SFF SAS/SATA drive cage
Note: Image shown without the security front bezel which is standard in every ML110 Gen11 unit.
I/O Diagram (Side)
Key
Component
1
CPU Socket with 16 DDR5 DIMM slots
2
M.2 Slot 2
3
M.2 Slot 1
4
x8 SlimSAS port
5
Megacell battery holder (Under)
6
HPE NS204i-u NVMe Hot Plug Boot Device (Optional)
7
Slot 14 OCP 1 (Optional for OROC/NIC)
8
Slot 4 PCIe5 x16
9
USB 2.0 port
10
Slot 1 PCIe5 x16
11
MCIO port 1 for the riser slot 2
12
MCIO port 2 for the riser slot 2
13
MCIO port 3 for the riser slot 3
14
MCIO port 4 for the riser slot 3
15
USB 3.2 Gen 1 port
I/O Diagram (Back)
Key
Component
1
HPE NS204i-u Gen11 NVMe Hot Plug Boot Device (Optional)
2
Flexible Slot power supply 1
3
Flexible Slot power supply 2
4
Slot 14 OCP 1 (Optional for OROC/NIC OCP adapter)
5
Serial port (Optional)
6
VGA Port
7
Dual USB 3.2 Gen 1 ports
8
iLO management port
9
Dual NIC ports (1 GbE)
10
Slot 1 PCIe5 x16
11
Slot 2 PCIe5 x16 (Optional riser kit required)
12
Slot 3 PCIe5 x16 (Optional riser kit required)
13
Slot 4 PCIe5 x16



