Enterprise-Class Power with SMB-Focused Flexibility
The HPE ProLiant ML350 Gen11 Tower Server is engineered to deliver dependable performance for small to mid-sized business environments. With a 16-core Intel Xeon Silver 4514Y processor, 64 GB DDR5 memory, and 4.8 TB of SAS storage out of the box, this server supports compute-heavy workloads while offering room to scale. Housed in a 4U tower chassis and backed by robust remote management via iLO 6, the ML350 Gen11 is an efficient and secure choice for IT infrastructure, virtualization, and data-centric tasks.
Key Features
Intel Xeon Silver 4514Y processor with 16 cores, 2.0 GHz base, and 3.4 GHz boost frequency
64 GB DDR5 memory at 5600 MHz, expandable to 8 TB across 32 DIMM slots
Dual 2.4 TB SAS HDDs (RAID capable), supporting up to 368.64 TB total storage
Broadcom BCM5719 LAN controller with four Gigabit Ethernet ports
PCIe Gen5 support for up to 10 expansion slots and high-performance GPU options
Redundant 2000 W power supply with 1 RPS installed for reliability
Trusted Platform Module (TPM) security and HPE’s Silicon Root of Trust firmware protection
Hot-pluggable RAID1 protected M.2 NVMe boot options available
Tool-less 4U black tower design with 712 mm depth and remote management via iLO 6
Built Around Intel Xeon Silver Performance
At the core is the 16-core Intel Xeon Silver 4514Y, balancing performance and efficiency with a 3.4 GHz max turbo frequency. Whether you're running ERP systems or virtual desktops, the ML350 Gen11 offers consistent multi-threaded performance with 30 MB of processor cache and a reliable Intel C741 chipset.
High-Speed Memory with Massive Expansion
Configured with 64 GB DDR5 memory (2 x 32 GB) running at 5600 MHz, this server is designed to grow with your business. With 32 DIMM slots, it supports a total memory capacity of up to 8 TB, delivering optimal throughput for database processing and virtualization.
Flexible SAS Storage and Scalable Capacity
Equipped with two 2.4 TB 2.5" SAS drives and supporting up to eight drives, the ML350 Gen11 is capable of achieving up to 368.64 TB of total storage. Combined with RAID support, this offers both performance and data resilience for demanding workloads.
Reliable Connectivity and Expansion
Networking is handled by a Broadcom BCM5719 controller with four RJ-45 Gigabit Ethernet ports. USB 3.2 and VGA outputs ensure quick local access, while PCIe Gen5 slots allow for expansion into graphics, networking, or storage-intensive domains.
Optimized Design and Power Resilience
Compact for its class at 174 mm wide and 462 mm high, this 4U tower fits comfortably into office or edge environments. A 2000 W power supply with redundant support ensures uninterrupted operation for critical applications.
Secure and Remote-Ready
The ML350 Gen11 integrates TPM for platform integrity and leverages HPE iLO 6 for streamlined remote management. From monitoring system health to deploying updates, control remains secure and accessible anytime, anywhere.
I/O Diagram (Front 4LFF "4 Bays")
Key
Component
1
DisplayPort 1.1a
2
USB 3.2 Gen1 port
3
iLO service port
4
UID button/LED
5
NIC status LED 1
6
Health LED
7
Power on/Standby button and system power LED
8
Optical drive bay
9
Media bay filler panel
10
Serial number/iLO information pull tab
11
Box3: Default drive cage for 4LFF
12
Box2: Optional drive cage for 8SFF/4LFF
13
Box1: Optional drive cage for 8SFF/4LFF, or internal LTO tape drive
Notes:1 Front NIC LED display doesn’t support NIC LED ACT/LINK indication from ALOM/PCIE/FLOM NIC's
I/O Diagram (Front 8SFF "8 Bays")
Key
Component
1
DisplayPort 1.1a
2
USB 3.2 Gen1 port
3
iLO service port
4
UID button/LED
5
NIC status LED
6
Health LED
7
Power on/Standby button and system power LED
8
Optical drive bay
9
Media bay filler panel
10
Serial number/iLO information pull tab
11
Box3: Default drive cage for 8SFF*
12
Box2: Optional drive cage for 8SFF
13
Box1: Optional drive cage for 8SFF, or internal LTO tape drive
Notes: *Optional for 8SFF x4 U.3 drive kit or 12 EDSFF drive kit
I/O Diagram (Side)
Key
Component
1
CPU Socket 1 & 2
2
Dual USB port (Stacked, Top: USB 3.2 Gen1 port, Bottom: USB 2.0 port)
3
Megacell battery holder (Under)
4
HPE NS204i-u Gen11 NVMe Hot Plug Boot Optimized Storage Device (Optional)
5
Secondary riser connector
6
Tertiary riser sideband connector
7
Serial port cable connector
8
Slot 15 OCP 2 (Optional for NIC adapter)
9
HPE NS204i-u power connector
10
Primary riser connector
11
Slot 14 OCP 1 (Optional for OROC/NIC adapter)
Notes:
1 CPU1 (bottom) shown Standard Heatsink with fully memory populated in 16 slots (32 slots in total)
2 CPU2 (top) shown Standard Heatsink with fully memory populated in 16 slots (32 slots in total)
I/O Diagram (Back)
Key
Component
1
HPE NS204i-u Gen11 NVMe Hot Plug Boot Optimized Storage Device (Optional)
2
PCIe Slots 9-10 (Optional tertiary riser, 2nd processor required for expansion card installation)
3
Flexible Slot power supply 1
4
Flexible Slot power supply 2 (Optional)
5
VGA Port
6
External Fan connector 9
7
Slot 15 OCP 2 (Optional for NIC adapter)
8
Serial port (Optional)
9
iLO management port
10
USB 3.2 Gen 1 ports x2
11
External Fan connector 10
12
Slot 14 OCP 1 (Optional for OROC/NIC adapter)
13
PCIe Slots 1-4 (Primary riser)
14
Padlock eye
15
PCIe Slots 5-8 (Secondary riser)
16
Kensington slot
The HPE ProLiant ML350 Gen11 (P81775-425) is a reliable, tower-optimized server built for small to mid-sized businesses seeking dependable performance, expandability, and security. Equipped with a single Intel Xeon Silver 4509Y processor, 64 GB of DDR5 memory, and dual 480 GB SSDs, this 4U tower server delivers efficient processing for general-purpose workloads, infrastructure management, and light virtualization. Designed to scale with your business, it includes 32 DIMM slots supporting up to 8 TB of memory and redundant power capabilities for uptime assurance.
Key Features:
Intel Xeon Silver 4509Y CPU with 8 cores, 2.6 GHz base and 4.1 GHz boost frequency
64 GB DDR5-SDRAM (2 x 32 GB), expandable up to 8 TB via 32 DIMM slots
Dual 480 GB 2.5" SATA III SSDs pre-installed; supports up to 8 drives
Broadcom BCM5719 controller with 4x Gigabit Ethernet ports for network connectivity
Includes hardware RAID support and Trusted Platform Module 2.0 security
Redundant 2x 1000W power supplies ensure consistent operation
Tool-less, 4U black tower chassis with optional rack conversion
Reliable Xeon Compute Power
Powered by a single Intel Xeon Silver 4509Y processor, the ML350 Gen11 balances core performance and thermal efficiency. With 8 cores and a max turbo frequency of 4.1 GHz, it supports essential applications and multitasking for IT environments that demand responsiveness without overconsumption.
Expandable DDR5 Memory Architecture
This configuration includes 64 GB of fast DDR5-SDRAM operating at 5600 MHz. With 32 DIMM slots available, the system supports memory expansion up to 8 TB, enabling seamless scaling for VMs, data processing, and future growth.
Enterprise-Grade Storage and RAID
Two pre-installed 480 GB SSDs provide a total of 960 GB of fast storage. RAID support is built in, and the system accommodates up to 8 2.5" drives, giving you flexibility in balancing performance, redundancy, and capacity.
Efficient Networking and Connectivity
Equipped with four Gigabit Ethernet ports via the Broadcom BCM5719 controller, the ML350 Gen11 ensures stable and redundant network access for business-critical applications and remote management setups.
Redundant Power and Secure Operation
Dual 1000W power supplies (redundant) minimize downtime risks, while integrated TPM 2.0 ensures secure system authentication. The server is shipped without an OS, allowing for customized deployment across Windows, Linux, or virtual environments.
I/O Diagram (Front 4LFF "4 Bays")
Key
Component
1
DisplayPort 1.1a
2
USB 3.2 Gen1 port
3
iLO service port
4
UID button/LED
5
NIC status LED 1
6
Health LED
7
Power on/Standby button and system power LED
8
Optical drive bay
9
Media bay filler panel
10
Serial number/iLO information pull tab
11
Box3: Default drive cage for 4LFF
12
Box2: Optional drive cage for 8SFF/4LFF
13
Box1: Optional drive cage for 8SFF/4LFF, or internal LTO tape drive
Notes:1 Front NIC LED display doesn’t support NIC LED ACT/LINK indication from ALOM/PCIE/FLOM NIC's
I/O Diagram (Front 8SFF "8 Bays")
Key
Component
1
DisplayPort 1.1a
2
USB 3.2 Gen1 port
3
iLO service port
4
UID button/LED
5
NIC status LED
6
Health LED
7
Power on/Standby button and system power LED
8
Optical drive bay
9
Media bay filler panel
10
Serial number/iLO information pull tab
11
Box3: Default drive cage for 8SFF*
12
Box2: Optional drive cage for 8SFF
13
Box1: Optional drive cage for 8SFF, or internal LTO tape drive
Notes: *Optional for 8SFF x4 U.3 drive kit or 12 EDSFF drive kit
I/O Diagram (Side)
Key
Component
1
CPU Socket 1 & 2
2
Dual USB port (Stacked, Top: USB 3.2 Gen1 port, Bottom: USB 2.0 port)
3
Megacell battery holder (Under)
4
HPE NS204i-u Gen11 NVMe Hot Plug Boot Optimized Storage Device (Optional)
5
Secondary riser connector
6
Tertiary riser sideband connector
7
Serial port cable connector
8
Slot 15 OCP 2 (Optional for NIC adapter)
9
HPE NS204i-u power connector
10
Primary riser connector
11
Slot 14 OCP 1 (Optional for OROC/NIC adapter)
Notes:
1 CPU1 (bottom) shown Standard Heatsink with fully memory populated in 16 slots (32 slots in total)
2 CPU2 (top) shown Standard Heatsink with fully memory populated in 16 slots (32 slots in total)
I/O Diagram (Back)
Key
Component
1
HPE NS204i-u Gen11 NVMe Hot Plug Boot Optimized Storage Device (Optional)
2
PCIe Slots 9-10 (Optional tertiary riser, 2nd processor required for expansion card installation)
3
Flexible Slot power supply 1
4
Flexible Slot power supply 2 (Optional)
5
VGA Port
6
External Fan connector 9
7
Slot 15 OCP 2 (Optional for NIC adapter)
8
Serial port (Optional)
9
iLO management port
10
USB 3.2 Gen 1 ports x2
11
External Fan connector 10
12
Slot 14 OCP 1 (Optional for OROC/NIC adapter)
13
PCIe Slots 1-4 (Primary riser)
14
Padlock eye
15
PCIe Slots 5-8 (Secondary riser)
16
Kensington slot
